Article
Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: the role of obesity and smoking.
Atherosclerosis - 1 May 2009
Panoulas Vasileios F, Stavropoulos-Kalinoglou Antonios, Metsios Giorgos S, Smith Jacqueline P, Milionis Haralampos J, Douglas Karen M J, Nightingale Peter, Kitas George D
Abstract excerpt
BACKGROUND: Cardiovascular morbidity and mortality are increased in rheumatoid arthritis (RA). Interleukin-6 (IL-6) is high in RA and, together with smoking and obesity, an important contributor to the development of cardiovascular disease (CVD). The present study examined the potential association of IL-6-174 G/C polymorphism, together with obesity and smoking, with the presence of CVD in RA patients. METHODS...
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