Article
Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria.
Haematologica - 1 Jun 2010
Mejstrikova Ester, Volejnikova Jana, Fronkova Eva, Zdrahalova Katerina, Kalina Tomas, Sterba Jaroslav, Jabali Yahia, Mihal Vladimir, Blazek Bohumir, Cerna Zdena, Prochazkova Daniela, Hak Jiri, Zemanova Zuzana, Jarosova Marie, Oltova Alexandra, Sedlacek Petr, Schwarz Jiri, Zuna Jan, Trka Jan, Stary Jan, Hrusak Ondrej
Abstract excerpt
BACKGROUND: Mixed phenotype acute leukemia (MPAL) represents a diagnostic and therapeutic dilemma. The European Group for the Immunological Classification of Leukemias (EGIL) scoring system unambiguously defines MPAL expressing aberrant lineage markers. Discussions surrounding it have focused on scoring details, and information is limited regarding its biological, clinical and prognostic significance. The recent...
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