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Article

Role of ACE and PAI-1 Polymorphisms in the Development and Progression of Diabetic Retinopathy.

PloS one - 1 Jan 2015

Saleem Saba, Azam Aisha, Maqsood Sundus Ijaz, Muslim Irfan, Bashir Shaheena, Fazal Nosheen, Riaz Moeen, Ali Syeda Hafiza Benish, Niazi Muhammad Khizar, Ishaq Mazhar, Waheed Nadia Khalida, Qamar Raheel, Azam Maleeha

Abstract excerpt

In the present study we determined the association of angiotensin converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms with diabetic retinopathy (DR) and its sub-clinical classes in Pakistani type 2 diabetic patients. A total of 353 diabetic subjects including 160 DR and 193 diabetic non retinopathy (DNR) as well as 198 healthy controls were genotyped by allele specific...

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Identifiers

PMID: 26658948
DOI: 10.1371/journal.pone.0144557
PMCID: PMC4679138

Genes

ACE

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Source receipt: pubmed, retrieved 7 Sept 2026.

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