Tangier disease and ABCA1.

Abstract excerpt

Tangier disease is an autosomal recessive genetic disorder characterized by a severe high-density lipoprotein (HDL) deficiency, sterol deposition in tissue macrophages, and prevalent atherosclerosis. Mutations in the ATP binding cassette transporter ABCA1 cause Tangier disease and other familial...

Topics

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• Apolipoproteins
• ATP Binding Cassette Transporter 1
• ATP-Binding Cassette Transporters
• Biological Transport
• Lipoproteins, HDL
• Macrophages