Article

Ageing restructures the basal transcriptome of the core hypothalamic osmoregulatory control centre and alters the response to dehydration

2023-02-15

Abstract excerpt

<title>Abstract</title> <p>Ageing is associated with altered neuroendocrine function. In the context of the hypothalamic supraoptic nucleus, which makes the antidiuretic hormone vasopressin, ageing alters acute responses to hyperosmotic cues, rendering the elderly more susceptible to dehydration. Chronically, vasopressin has been associated with numerous diseases of old age, including type 2 diabetes and metaboli...

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Literature Corpus work: 136a5567-ea74-5672-b060-ec189b741af8
DOI: 10.21203/rs.3.rs-2463463/v1

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