Article
Interleukin-6-174 G/C polymorphism is not associated with IL-6 expression and susceptibility to sporadic colon cancer.
DNA and cell biology - 1 Apr 2010
Cacev Tamara, Jokić Mladen, Loncar Bozo, Krizanac Simun, Kapitanović Sanja
Abstract excerpt
Interleukin-6 (IL-6) has been implicated in tumorigenesis; however, its role is still far from being clearly defined. Regulation of IL-6 expression is highly complex, and additional complexity is introduced by single-nucleotide polymorphisms in the IL-6 gene. These single-nucleotide polymorphisms might influence mRNA transcription, which might in turn result in increased susceptibility to certain tumors. The aim...
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