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Article

TNFα gene/protein in tumorigenesis of sporadic colon adenocarcinoma.

Experimental and molecular pathology - 1 Oct 2014

Kapitanović Sanja, Čačev Tamara, Catela Ivković Tina, Lončar Božo, Aralica Gorana

Abstract excerpt

PURPOSE: Inherited polymorphisms in immunomodulatory genes such as cytokines may contribute to variation in immunological response and genetic susceptibility for complex diseases, including cancer. TNFα can mediate tumor progression by inducing proliferation, invasion and metastasis of tumor cells. The aim of our study was to examine the allelic frequencies of TNFα promoter SNPs, -1031 T/C, -857 C/T, -308 G/A and...

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Source

Identifiers

PMID: 25102301
DOI: 10.1016/j.yexmp.2014.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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