Interleukin-6 -174 G/C promoter polymorphism and nasal polyposis.

doi:10.4193/Rhin08.226

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Article

Interleukin-6 -174 G/C promoter polymorphism and nasal polyposis.

Rhinology - 1 Dec 2009

Kosugi Eduardo Macoto, de Camargo-Kosugi Cínta Meirelles, Weckx Luc Louis Maurice, Guerreiro-da-Silva Ismael Dale Cotrim, Gregorio Luiz Carlos

Abstract excerpt

INTRODUCTION: Nasal polyposis is a chronic disease with unknown etiopathogenesis, although inflammatory mechanisms seem to play a role. One of several inflammatory mediators linked to nasal polyposis is Interleukin-6, which has a single nucleotide polymorphism -174 G/C that seems to promote an inflammatory reaction. OBJECTIVE: To compare the prevalence of the -174 G/C single nucleotide polymorphism between a...

Topics

Adult
Aged
Cross-Sectional Studies
DNA Fragmentation
Electrophoresis, Agar Gel
Female
Genotype
Humans
Interleukin-6
Male
Middle Aged
Nasal Polyps
Polymorphism, Single Nucleotide

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Open in PubMed

Identifiers

PMID: 19936367
DOI: 10.4193/Rhin08.226

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