Article
Interleukin-6 -174 G/C promoter polymorphism and nasal polyposis.
Rhinology - 1 Dec 2009
Kosugi Eduardo Macoto, de Camargo-Kosugi Cínta Meirelles, Weckx Luc Louis Maurice, Guerreiro-da-Silva Ismael Dale Cotrim, Gregorio Luiz Carlos
Abstract excerpt
INTRODUCTION: Nasal polyposis is a chronic disease with unknown etiopathogenesis, although inflammatory mechanisms seem to play a role. One of several inflammatory mediators linked to nasal polyposis is Interleukin-6, which has a single nucleotide polymorphism -174 G/C that seems to promote an inflammatory reaction. OBJECTIVE: To compare the prevalence of the -174 G/C single nucleotide polymorphism between a...
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