Article
C. elegans Kallmann syndrome protein KAL-1 interacts with syndecan and glypican to regulate neuronal cell migrations.
Developmental biology - 15 Jun 2006
Hudson Martin L, Kinnunen Tarja, Cinar Hediye Nese, Chisholm Andrew D
Abstract excerpt
The anosmin-1 protein family regulates cell migration, axon guidance, and branching, by mechanisms that are not well understood. We show that the C. elegans anosmin-1 ortholog KAL-1 promotes migrations of ventral neuroblasts prior to epidermal enclosure. KAL-1 does not modulate FGF signaling in neuroblast migration and acts in parallel to other neuroblast migration pathways. Defects in heparan sulfate (HS)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
