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Article

Genetic diagnosis of familial breast cancer using clonal sequencing.

Human mutation - 1 Apr 2010

Morgan Joanne E, Carr Ian M, Sheridan Eamonn, Chu Carol E, Hayward Bruce, Camm Nick, Lindsay Helen A, Mattocks Chris J, Markham Alexander F, Bonthron David T, Taylor Graham R

Abstract excerpt

Using conventional Sanger sequencing as a reference standard, we compared the sensitivity, specificity, and capacity of the Illumina GA II platform for the detection of TP53, BRCA1, and BRCA2 mutations in established tumor cell lines and DNA from patients with germline mutations. A total of 656 c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20127978
DOI: 10.1002/humu.21216

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20127978-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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