Article
Estimating genome-wide heterozygosity: effects of demographic history and marker type.
Heredity - 1 Mar 2014
Miller J M, Malenfant R M, David P, Davis C S, Poissant J, Hogg J T, Festa-Bianchet M, Coltman D W
Abstract excerpt
Heterozygosity-fitness correlations (HFCs) are often used to link individual genetic variation to differences in fitness. However, most studies examining HFCs find weak or no correlations. Here, we derive broad theoretical predictions about how many loci are needed to adequately measure genomic heterozygosity assuming different levels of identity disequilibrium (ID), a proxy for inbreeding. We then evaluate the...
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