Article
Does narcolepsy symptom severity vary according to HLA-DQB1*0602 allele status?
Sleep - 1 Jan 2010
Watson Nathaniel F, Ton Thanh G N, Koepsell Thomas D, Gersuk Vivian H, Longstreth W T
Abstract excerpt
STUDY OBJECTIVES: To investigate associations between HLA-DQB1*0602 allele status and measures of narcolepsy symptom severity. DESIGN: Cross-sectional study of population-based narcolepsy patients. SETTING: King County, Washington. PARTICIPANTS: All prevalent cases (n = 279) of physician-diagnosed narcolepsy ascertained from 2001-2005. INTERVENTIONS: N/A. MEASUREMENTS: Narcolepsy diagnosis was based on cataplexy...
Topics
- Adult
- Aged
- Alleles
- Cataplexy
- Cross-Sectional Studies
- Female
- Gene Frequency
- Genetic Carrier Screening
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Linear Models
- Male
- Membrane Glycoproteins
- Middle Aged
- Narcolepsy
