Article
Blocking angiotensin II Type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells.
Pancreas - 1 Jul 2010
Gong Qiaoke, Davis Molly, Chipitsyna Galina, Yeo Charles J, Arafat Hwyda A
Abstract excerpt
OBJECTIVES: Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy with an annual mortality rate close to its annual incidence. We recently demonstrated that angiotensin II (AngII) type 1 receptor (AT1R) might be involved in PDA angiogenesis. This study evaluated the antiproliferative...
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