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Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells

7 May 2010

Abstract excerpt

Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide. In addition to the poor survival rates, combinations using gemcitabine as a backbone have failed to show any benefit beyond monotherapy. These facts underscore an urgent need for novel therapeutic options and motivated us to study the effect of berberine on pancreatic cancer cells. Here, we undertook an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20455200
DOI: 10.1055/s-0030-1249931

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