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Article

SOX2 has gender-specific genetic effects on diabetic nephropathy in samples from patients with type 1 diabetes mellitus in the GoKinD study.

Gender medicine - 1 Dec 2009

Gu Harvest F, Alvarsson Alexandra, Efendic Suad, Brismar Kerstin

Abstract excerpt

BACKGROUND: Sex-determining region Y-box 2 (SOX2) is a transcription factor that plays an important role in the induction of pluripotent stem cells from somatic cells. The SOX2 gene is located in chromosome 3q26.33, in the linkage region of diabetes and diabetic nephropathy (DN). Evidence indicates that SOX2 is expressed in the adult human pancreas. OBJECTIVE: This study investigated whether SOX2 is involved in...

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Topics

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Share to Adiponectin
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Gene Frequency

Share to Kidney Failure, Chronic

Share to Promoter Regions, Genetic

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Share to SOXB1 Transcription Factors

Source

Identifiers

PMID: 20114006
DOI: 10.1016/j.genm.2009.11.001

Genes

SOX2

Provenance

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