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Article

Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus.

BMC medical genetics - 28 Jul 2010

Zhang Dongying, Efendic Suad, Brismar Kerstin, Gu Harvest F

Abstract excerpt

BACKGROUND: MCF2L2, ADIPOQ and SOX2 genes are located in chromosome 3q26-27, which is linked to diabetic nephropathy (DN). ADIPOQ and SOX2 genetic polymorphisms are found to be associated with DN. In the present study, we first investigated the association between MCF2L2 and DN, and then evaluated effects of these three genes on the development of DN. METHODS: A total of 1177 type 1 diabetes patients with and...

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Source

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Identifiers

PMID: 20667095
DOI: 10.1186/1471-2350-11-116
PMCID: PMC2919463

Genes

ADIPOQ
SOX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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