Article
Evaluation of Sox2 genetic effect on the development of type 2 diabetes.
Gene - 15 Oct 2011
Gu Harvest F, Gu Tianwei, Ostenson Claes-Göran, Kärvestedt Lars, Brismar Kerstin
Abstract excerpt
Sox2 is a transcription factor, which plays an important role in the induction of pluripotent stem cells from somatic cells. The Sox2 gene is located in chromosome 3q26.33 and resides in a linkage region of diabetes. In the present study, we attempted to evaluate the genetic effect of Sox2 in the development of type 2 diabetes (T2D). A total of 1598 Swedish subjects of T2D, pre-diabetes and non-diabetic control...
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