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Article

Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy.

Journal of translational medicine - 29 Jan 2010

Monsurrò Vladia, Beghelli Stefania, Wang Richard, Barbi Stefano, Coin Silvia, Di Pasquale Giovanni, Bersani Samantha, Castellucci Monica, Sorio Claudio, Eleuteri Stefano, Worschech Andrea, Chiorini Jay A, Pederzoli Paolo, Alter Harvey, Marincola Francesco M, Scarpa Aldo

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer mortality for which novel gene therapy approaches relying on tumor-tropic adenoviruses are being tested. METHODS: We obtained the global transcriptional profiling of primary PDAC using RNA from eight xenografted...

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Share to Adenoviridae
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20113473
DOI: 10.1186/1479-5876-8-10
PMCID: PMC2845551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20113473-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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