Article
Immunological mutational signature in adenosquamous cancer of pancreas: an exploratory study of potentially therapeutic targets.
Expert opinion on therapeutic targets - 1 May 2018
Silvestris Nicola, Brunetti Oronzo, Pinto Rosamaria, Petriella Daniela, Argentiero Antonella, Fucci Livia, Tommasi Stefania, Danza Katia, De Summa Simona
Abstract excerpt
OBJECTIVES: Adenosquamous cancer of pancreas (ASCP) is a rare variant of pancreatic adenocarcinoma (PDAC). It is characterized by poor prognosis and lacks of literature data supporting the choice of systemic therapies. The role of immunotherapy for this malignancy is still unknown. In this study, we evaluated any differences between immune-related genes of PDAC and its adenosquamous variant with the aim to...
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