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Article

The roles of interferon regulatory factors 1 and 2 in the progression of human pancreatic cancer.

Pancreas - 1 Aug 2014

Sakai Toshitaka, Mashima Hirosato, Yamada Yumi, Goto Takashi, Sato Wataru, Dohmen Takahiro, Kamada Kentaro, Yoshioka Masato, Uchinami Hiroshi, Yamamoto Yuzo, Ohnishi Hirohide

Abstract excerpt

OBJECTIVE: Pancreatic cancer is one of the most malignant diseases worldwide. Interferon regulatory factor (IRF) 1 and IRF2 function as a tumor suppressor and oncoprotein, respectively, in several types of cancers. We investigated whether IRF1 and IRF2 are involved in the progression of pancreatic cancer. METHODS: We examined the expressions of IRF1 and IRF2 in pancreatic cancer specimens and analyzed the...

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PMID: 24632547
DOI: 10.1097/MPA.0000000000000116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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