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Article

Phosphorylated p27Kip1 on Thr157 is an important prognosis in human hepatocellular carcinoma in vivo and in vitro.

Medical oncology (Northwood, London, England) - 1 Mar 2011

He Song, Lu Mudan, Xue Wenqun, Wang You, Zhao Yueming, Gao Shangfeng, Ke Qing, Liu Yonghua, Li Peng, Cui Xiaopeng, Cheng Chun, Shen Aiguo

Abstract excerpt

The p27(Kip1) cyclin-dependent kinase inhibitor is a negative regulator of cell cycle progression in G(1) phase; recent studies suggested that oncogenically activated kinase Akt/PKB can also phosphorylate p27(kip1) at T157 inducing its relocalization to the cytoplasm. To evaluate the significance...

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PMID: 20108172
DOI: 10.1007/s12032-009-9408-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20108172-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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