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Article

Effect of mutant p27(kipl) gene on human cholangiocarcinoma cell line, QBC(939).

World journal of gastroenterology - 14 Sept 2008

Luo Jian, Chen Yong-Jun, Wang Wei-Yu, Zou Sheng-Quan

Abstract excerpt

AIM: To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS: Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growth, morphological change, cell cycle, apoptosis and cloning formation were determined by MTT...

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Identifiers

PMID: 18785290
DOI: 10.3748/wjg.14.5344
PMCID: PMC2744068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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