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Article

Hemodynamic environments from opposing sides of human aortic valve leaflets evoke distinct endothelial phenotypes in vitro.

Cardiovascular engineering (Dordrecht, Netherlands) - 1 Mar 2010

Weinberg Eli J, Mack Peter J, Schoen Frederick J, García-Cardeña Guillermo, Kaazempur Mofrad Mohammad R

Abstract excerpt

The regulation of valvular endothelial phenotypes by the hemodynamic environments of the human aortic valve is poorly understood. The nodular lesions of calcific aortic stenosis (CAS) develop predominantly beneath the aortic surface of the valve leaflets in the valvular fibrosa layer. However, th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20107896
DOI: 10.1007/s10558-009-9089-9
PMCID: PMC2837826

Genes

KLF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20107896-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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