Article
Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats.
Veterinary research - 9 Apr 2014
Kanata Eirini, Humphreys-Panagiotidis Cynthia, Giadinis Nektarios D, Papaioannou Nikolaos, Arsenakis Minas, Sklaviadis Theodoros
Abstract excerpt
The present study investigates the potential use of the scrapie-protective Q211 S146 and K222 caprine PRNP alleles as targets for selective breeding in Greek goats. Genotyping data from a high number of healthy goats with special emphasis on bucks, revealed high frequencies of these alleles, while the estimated probabilities of disease occurrence in animals carrying these alleles were low, suggesting that they...
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