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Article

Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents.

Diabetes - 1 Apr 2010

Georgia Senta, Hinault Charlotte, Kawamori Dan, Hu Jiang, Meyer John, Kanji Murtaza, Bhushan Anil, Kulkarni Rohit N

Abstract excerpt

OBJECTIVE: A major determinant of the progression from insulin resistance to the development of overt type 2 diabetes is a failure to mount an appropriate compensatory beta-cell hyperplastic response to maintain normoglycemia. We undertook the present study to directly explore the significance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20103709
DOI: 10.2337/db09-0838
PMCID: PMC2844846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20103709-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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