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Article

Cyclin D2 protein stability is regulated in pancreatic beta-cells.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2009

He Lu Mei, Sartori Daniel J, Teta Monica, Opare-Addo Lynn M, Rankin Matthew M, Long Simon Y, Diehl J Alan, Kushner Jake A

Abstract excerpt

The molecular determinants of beta-cell mass expansion remain poorly understood. Cyclin D2 is the major D-type cyclin expressed in beta-cells, essential for adult beta-cell growth. We hypothesized that cyclin D2 could be actively regulated in beta-cells, which could allow mitogenic stimuli to inf...

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Identifiers

PMID: 19628581
DOI: 10.1210/me.2009-0057
PMCID: PMC2775938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19628581-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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