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Article

Modeling complex genetic and environmental influences on comorbid bipolar disorder with tobacco use disorder.

BMC medical genetics - 26 Jan 2010

McEachin Richard C, Saccone Nancy L, Saccone Scott F, Kleyman-Smith Yelena D, Kar Tiara, Kare Rajesh K, Ade Alex S, Sartor Maureen A, Cavalcoli James D, McInnis Melvin G

Abstract excerpt

BACKGROUND: Comorbidity of psychiatric and substance use disorders represents a significant complication in the clinical course of both disorders. Bipolar Disorder (BD) is a psychiatric disorder characterized by severe mood swings, ranging from mania to depression, and up to a 70% rate of comorbid Tobacco Use Disorder (TUD). We found epidemiological evidence consistent with a common underlying etiology for BD and...

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Identifiers

PMID: 20102619
DOI: 10.1186/1471-2350-11-14
PMCID: PMC2823619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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