Article
Shared genetic factors influence risk for bipolar disorder and alcohol use disorders.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Jun 2014
Carmiol N, Peralta J M, Almasy L, Contreras J, Pacheco A, Escamilla M A, Knowles E E M, Raventós H, Glahn D C
Abstract excerpt
Bipolar disorder and alcohol use disorder (AUD) have a high rate of comorbidity, more than 50% of individuals with bipolar disorder also receive a diagnosis of AUD in their lifetimes. Although both disorders are heritable, it is unclear if the same genetic factors mediate risk for bipolar disorder and AUD. We examined 733 Costa Rican individuals from 61 bipolar pedigrees. Based on a best estimate process, 32% of...
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