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Article

Preimplantation genetic diagnosis for hemophilia A using indirect linkage analysis and direct genotyping approaches.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2010

Laurie A D, Hill A M, Harraway J R, Fellowes A P, Phillipson G T, Benny P S, Smith M P, George P M

Abstract excerpt

BACKGROUND: Preimplantation genetic diagnosis (PGD) is an appealing option for couples at risk of having a child with hemophilia A (HA). Although many clinics offer PGD for HA by gender selection, an approach that detects the presence of the underlying F8 mutation has several advantages. OBJECTIVES: To develop and validate analysis protocols combining indirect and direct methods for identifying F8 mutations in...

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Identifiers

PMID: 20102489
DOI: 10.1111/j.1538-7836.2010.03768.x

Genes

PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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