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Article

A versatile strategy for preimplantation genetic diagnosis of haemophilia A based on F8-gene sequencing.

Thrombosis and haemostasis - 1 Dec 2006

Sánchez-García Jorge F, Gallardo Dominique, Navarro Joaquima, Márquez Carmen, Gris Josep Maria, Sánchez Maria Angeles, Altisent Carme, Vidal Francisco

Abstract excerpt

Preimplantation genetic diagnosis (PGD) of hemophilia A (HA) and other X-linked diseases through sex selection implies that male embryos will be systematically discarded, even though 50% are unaffected. The objective of the present work was to develop a PGD protocol for direct mutation identification that could be applied to first polar bodies (1PBs) in several HA clinical cases. Single buccal cells from controls...

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PMID: 17139381

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PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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