Article
Strategies and clinical outcome of 250 cycles of Preimplantation Genetic Diagnosis for single gene disorders.
Human reproduction (Oxford, England) - 1 Mar 2006
Fiorentino F, Biricik A, Nuccitelli A, De Palma R, Kahraman S, Iacobelli M, Trengia V, Caserta D, Bonu M A, Borini A, Baldi M
Abstract excerpt
BACKGROUND: We report on our experience with preimplantation genetic diagnosis (PGD) for single gene disorders (SGDs), from 1999 to 2004, describing strategies and overall clinical outcome of 250 cycles in 174 couples for 23 different genetic conditions. METHODS: PGD cycles included 15 for autosomal dominant, 148 for autosomal recessive and 19 for X-linked SGDs. In addition, 68 cycles of PGD for SGDs were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.