Article
Identification of an endogenous substrate of zebrafish doublecortin-like protein kinase using a highly active truncation mutant.
Journal of biochemistry - 1 May 2010
Shimomura Sachiko, Nagamine Tadashi, Hatano Naoya, Sueyoshi Noriyuki, Kameshita Isamu
Abstract excerpt
Doublecortin-like protein kinase (DCLK), a Ser/Thr protein kinase predominantly expressed in brain and eyes, is believed to play crucial roles in neuronal functions. However, the regulatory mechanisms for DCLK activation and its physiological targets are still unknown. In the present study, we fo...
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