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Article

Many families of C. elegans microRNAs are not essential for development or viability.

Current biology : CB - 23 Feb 2010

Alvarez-Saavedra Ezequiel, Horvitz H Robert

Abstract excerpt

MicroRNAs (miRNAs) are approximately 23 nt regulatory RNAs that posttranscriptionally inhibit the functions of protein-coding mRNAs. We previously found that most C. elegans miRNAs are individually not essential for development or viability and proposed that paralogous miRNAs might often function redundantly. To test this hypothesis, we generated mutant C. elegans strains that each lack multiple or all members of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20096582
DOI: 10.1016/j.cub.2009.12.051
PMCID: PMC2844791

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Source receipt: pubmed, retrieved 7 Sept 2026.

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