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Article

Biophysical characterization and mutational analysis of the antibiotic resistance protein NimA from Deinococcus radiodurans.

Biochimica et biophysica acta - 1 Apr 2010

Leiros Hanna-Kirsti S, Brandsdal Bjørn Olav, McSweeney Seán M

Abstract excerpt

Metronidazole (MTZ) is an antibiotic commonly used to treat anaerobic bacterial infections in humans and animals. Antibiotic resistance toward this class of 5-nitroimidazole (5-Ni) drug derivatives has been related to the Nim genes thought to encode a reductase. Here we report the biophysical cha...

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Source

Identifiers

PMID: 20096385
DOI: 10.1016/j.bbapap.2010.01.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20096385-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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