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Article

S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle.

The Biochemical journal - 15 Mar 2010

Woo Jin Seok, Hwang Ji-Hye, Ko Jae-Kyun, Weisleder Noah, Kim Do Han, Ma Jianjie, Lee Eun Hui

Abstract excerpt

JPs (junctophilins) contribute to the formation of junctional membrane complexes in muscle cells by physically linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes. In humans with HCM (hypertrophic cardiomyopathy), mutations in JP2 are linked to altered Ca2+ signalli...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20095964
DOI: 10.1042/BJ20091225

Genes

TRPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20095964-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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