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Article

Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells.

The American journal of pathology - 1 Mar 2010

Poliani Pietro Luigi, Kisand Kai, Marrella Veronica, Ravanini Maria, Notarangelo Luigi Daniele, Villa Anna, Peterson Pärt, Facchetti Fabio

Abstract excerpt

Autoimmune regulator (AIRE) modulates the expression of tissue-restricted antigens (TSAs) and promotes central tolerance in the thymus. However, few autoreactive T cells escape negative selection and reach the periphery, where peripheral tolerance is required to avoid autoimmunity. Murine lymph n...

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Share to AIRE Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Tolerance

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Source

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Identifiers

PMID: 20093495
DOI: 10.2353/ajpath.2010.090956
PMCID: PMC2832133

Genes

AIRE
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20093495-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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