Article
The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions.
Genetic epidemiology - 1 May 2010
Cornelis Marilyn C, Agrawal Arpana, Cole John W, Hansel Nadia N, Barnes Kathleen C, Beaty Terri H, Bennett Siiri N, Bierut Laura J, Boerwinkle Eric, Doheny Kimberly F, Feenstra Bjarke, Feingold Eleanor, Fornage Myriam, Haiman Christopher A, Harris Emily L, Hayes M Geoffrey, Heit John A, Hu Frank B, Kang Jae H, Laurie Cathy C, Ling Hua, Manolio Teri A, Marazita Mary L, Mathias Rasika A, Mirel Daniel B, Paschall Justin, Pasquale Louis R, Pugh Elizabeth W, Rice John P, Udren Jenna, van Dam Rob M, Wang Xiaojing, Wiggs Janey L, Williams Kayleen, Yu Kai
Abstract excerpt
Genome-wide association studies (GWAS) have emerged as powerful means for identifying genetic loci related to complex diseases. However, the role of environment and its potential to interact with key loci has not been adequately addressed in most GWAS. Networks of collaborative studies involving different study populations and multiple phenotypes provide a powerful approach for addressing the challenges in...
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