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Article

Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat.

PloS one - 15 Jan 2010

Cheli Yann, Williams Shirley A, Ballotti Robert, Nugent Diane J, Kunicki Thomas J

Abstract excerpt

BACKGROUND: We have identified a cytosine-adenosine (CA) repeat length polymorphism in the 5'-regulatory region of the human integrin alpha2 gene ITGA2 that begins at -605. Our objective was to establish the contribution of this polymorphism to the regulation of integrin alpha2beta1 expression, w...

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Share to Adenosine
Share to Cell Line
Share to Chromatography, Affinity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosine

Share to Integrin alpha2

Share to Poly(ADP-ribose) Polymerases

Share to Protein Binding

Share to Repetitive Sequences, Nucleic Acid

Source

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Identifiers

PMID: 20090957
DOI: 10.1371/journal.pone.0008743
PMCID: PMC2806922

Genes

ITGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20090957-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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