The transcriptional programme of contact‐inhibition

Abstract excerpt

Abstract Proliferation of non‐transformed cells is regulated by cell–cell contacts, which are referred to as contact‐inhibition. Vice versa, transformed cells are characterised by a loss of contact‐inhibition. Despite its generally accepted importance for cell‐cycle control, little is known about the intracellular signalling pathways involved in contact‐inhibition. Unravelling the molecular mechanisms of...

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