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Article

AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2.

Traffic (Copenhagen, Denmark) - 1 May 2010

Pedersen Gitte Albinus, Chakraborty Souvik, Steinhauser Amie L, Traub Linton M, Madsen Mette

Abstract excerpt

Cubam is a multi-ligand receptor involved in dietary uptake of intrinsic factor-vitamin B(12) in the small intestine and reabsorption of various low-molecular-weight proteins (such as albumin, transferrin, apolipoprotein A-I and vitamin D-binding protein) in the kidney. Cubam is composed of two proteins: cubilin and amnionless. Cubilin harbors ligand binding capabilities, while amnionless provides membrane...

Read the complete abstract on PubMed

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Share to Adaptor Proteins, Vesicular Transport
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20088845
DOI: 10.1111/j.1600-0854.2010.01042.x
PMCID: PMC2964065

Genes

AMN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2.PMID 20088845Read ↗

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The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinerySemantic proximity Read ↗

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