Article
Gender-related distribution of the interleukin-1 beta and interleukin-1 receptor antagonist gene polymorphisms in patients with end-stage liver disease.
Inflammation - 1 Aug 2010
Fontanini Elisabetta, Cussigh Annarosa, Fabris Carlo, Falleti Edmondo, Toniutto Pierluigi, Bitetto Davide, Cmet Sara, Fumolo Elisa, Fornasiere Ezio, Bignulin Sara, Pinato David J, Minisini Rosalba, Pirisi Mario
Abstract excerpt
Interleukin-1 beta (IL-1 beta) genetic polymorphisms and IL-1 receptor antagonist (IL1RN) variable number tandem repeat (VNTR) seem to be related with the occurrence of chronic diseases. This study aimed to verify whether IL-1 beta -511>C/T, -31>T/C, +3953>C/T and IL1RN VNTR were associated to the development of liver cirrhosis. Two hundred forty cirrhotic patients were involved in the study. A significant trend...
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