Article
Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism.
Journal of virology - 1 Sept 2006
Paladino Natalia, Fainboim Hugo, Theiler Graciela, Schroder Teresa, Muñoz Alberto Eduardo, Flores Ana Claudia, Galdame Omar, Fainboim Leonardo
Abstract excerpt
Elevated levels of interleukin 10 (IL-10) were previously described for chronically hepatitis C virus (HCV)-infected patients. We determined by a sequence-specific oligonucleotide probing technique the IL-10 promoter genotypes in 286 Argentinean HCV patients grouped according to disease outcome. The GG genotype (position -1082) is known to be associated with high IL-10 production, GA is considered an intermediate...
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