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Article

GroEL dependency affects codon usage--support for a critical role of misfolding in gene evolution.

Molecular systems biology - 1 Jan 2010

Warnecke Tobias, Hurst Laurence D

Abstract excerpt

It has recently been suggested that the use of optimal codons limits mistranslation-induced protein misfolding, yet evidence for this remains largely circumstantial. In contrast, molecular chaperones have long been recognized to play crucial roles in misfolding prevention and remedy. We propose t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20087338
DOI: 10.1038/msb.2009.94
PMCID: PMC2824523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20087338-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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