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Article

Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.

PloS one - 13 Jan 2010

Nakano Michiko M, Lin Ann, Zuber Cole S, Newberry Kate J, Brennan Richard G, Zuber Peter

Abstract excerpt

BACKGROUND: Spx, an ArsC (arsenate reductase) family member, is a global transcriptional regulator of the microbial stress response and is highly conserved amongst Gram-positive bacteria. Bacillus subtilis Spx protein exerts positive and negative control of transcription through its interaction with the C-terminal domain of the RNA polymerase (RNAP) alpha subunit (alphaCTD). Spx activates trxA (thioredoxin) and...

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Identifiers

PMID: 20084284
DOI: 10.1371/journal.pone.0008664
PMCID: PMC2801614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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