Article
Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy.
Clinical and experimental pharmacology & physiology - 1 May 2010
Nicolazzo Joseph A, Steuten Jessica A, Charman Susan A, Taylor Nerida, Davies Philip J, Petrou Steven
Abstract excerpt
1. Although many studies have assessed changes to brain uptake of anti-epileptic drugs (AEDs) in chemically and electrically induced seizure models, there are limited data available on changes to brain uptake of AEDs in spontaneous seizure animal models, such as genetic absence epilepsy. 2. In th...
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