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Article

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects.

Trends in genetics : TIG - 1 Feb 2010

Sleegers Kristel, Lambert Jean-Charles, Bertram Lars, Cruts Marc, Amouyel Philippe, Van Broeckhoven Christine

Abstract excerpt

The recent discoveries in genome-wide association studies (GWAS) of novel susceptibility loci (CLU, CR1 and PICALM) for Alzheimer's disease (AD) have elicited considerable interest in the AD community. But what are the implications of these purely epidemiological findings for our understanding of disease etiology and patient care? In this review, we attempt to place these findings in the context of current and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20080314
DOI: 10.1016/j.tig.2009.12.004

Genes

CLU
PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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