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BDNF and Cortisol integrative system – Plasticity vs. degeneration: Implications of the Val66Met polymorphism

16 Aug 2019

Abstract excerpt

BDNF is the neurotrophin mediating pro-neuronal survival and plasticity. Cortisol (COR), in turn, is engaged in the coordination of several processes in the brain homeostasis. Stress-responsive, both factors show an integrative role through their receptor's dynamics in neurophysiology. Furthermore, the Val66Met BDNF polymorphism may play a role in this mechanism. AIM: to investigate BDNF-COR interaction in the...

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PMID: 31425696
DOI: 10.1016/j.yfrne.2019.100784

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