Article
Delineating the impact of neuroantigen vs genetic diversity on MP4-induced EAE of C57BL/6 and B6.129 mice.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 2009
Kuerten Stefanie, Rodi Michael, Javeri Sita, Gruppe Traugott L, Tary-Lehmann Magdalena, Lehmann Paul V, Addicks Klaus
Abstract excerpt
MBP-PLP fusion protein (MP4)-induced experimental autoimmune encephalomyelitis (EAE) is a model for multiple sclerosis (MS) that encompasses both a time-dependent attack on central nervous system (CNS) regions and a B cell component, mirroring important features of human multiple sclerosis. Compa...
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