Article
Genetic variation in osteopontin gene is associated with susceptibility to sarcoidosis in Slovenian population.
Disease markers - 1 Jan 2009
Maver A, Medica I, Salobir B, Tercelj M, Peterlin B
Abstract excerpt
Sarcoidosis is a systemic inflammatory disease characterised by appearance of granulomas. Precise etiology has not been elucidated. Osteopontin (Opn) is a Th1 cytokine whose levels have been found increased in granulomas and serum samples from patients with sarcoidosis. We investigated whether genetic variation in Osteopontin gene (OPN) gene contributes to susceptibility to sarcoidosis. Haplotype-block structure...
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