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Article

The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis.

PloS one - 1 Jan 2017

Lavi Hadas, Assayag Miri, Schwartz Assaf, Arish Nissim, Fridlender Zvi G, Berkman Neville

Abstract excerpt

BACKGROUND: Sarcoidosis is a systemic inflammatory disease of unknown etiology. Osteopontin (SPP1, OPN) is an extra cellular matrix glycoprotein and cytokine with a known role in granuloma formation and in autoimmune and inflammatory diseases. OBJECTIVE: To determine whether plasma OPN levels are elevated in patients with sarcoidosis and compare the frequency of four single nucleotide polymorphism (SNPs) variants...

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Identifiers

PMID: 28253271
DOI: 10.1371/journal.pone.0171945
PMCID: PMC5333822

Genes

CRP
SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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